Non-digestible oligosaccharides directly regulate host kinome to modulate host inflammatory responses without alterations in the gut microbiota

Data
repository for:

Wu RY, Määttänen
P, Napper S, Scruten E, Li B, Koike Y, Johnson-Henry KC, Pierro A, Rossi L, Botts
SR, Surette MG, Sherman PM. Non-digestible
oligosaccharides directly regulate host kinome to modulate host inflammatory
responses without alterations in the gut microbiota. Microbiome. 2017;5:135.

Available at: https://doi.org/10.1186/s40168-017-0357-4
Repository
information:

PSWY
FASTQ sequence files - 16S rRNA gene sequence files for P10 mice exposed to
lipopolysaccharide (LPS) and non-digestible oligosaccharides (inulin and scFOS)

16S_metadata.txt
- describes 16S rRNA gene sequence files

16S_preprocessed_sequences.fna
- preprocessed sequence file for 16S rRNA gene data (quality filtering, chimera
checking, etc.)

16S_otu_table_host_singleton_filtered_unrarified.biom
- OTU table for 16S rRNA gene sequence analysis before rarefaction

16S_otu_table_host_singleton_filtered_sd9194.biom
- OTU table for 16S rRNA gene sequence analysis after rarefaction to 9,194 OTU
counts/sample

16S_PICRUSt_analysis_code.txt
- commands for PICRUSt functional metagenome prediction

kinome_array_data.txt
- raw kinome array data for Caco-2Bbe1 cells exposed to non-digestible
oligosaccharides (inulin and scFOS) and challenged with enterohemorrhagic Escherichia
coli (EHEC)

kinome_array_metadata.txt
- describes raw kinome array data

kinome_array_PIIKA_2_parameters.txt
- PIIKA 2 parameters for kinome array analysis