Additional file 4 of Zearalenone disturbs the reproductive-immune axis in pigs: the role of gut microbial metabolites

Additional file 4: Supp Table S3-1. List of differentially expressed genes (DEGs) between control (Ctrl) and zearalenone (ZEN) treatment group in pre-starter pig’s uterus, thymus, spleen, liver and inguinal lymph nodes. Supp Table S3-2. List of DEGs between Ctrl and ZEN treatment group in starter pig’s uterus, thymus, spleen, liver, inguinal lymph nodes and ovary. Supp Table S3-3. GO classification and enrichment of overlapping up-regulated genes between pre-starter and starter pig’s uterus. Supp Table S3-4. GO classification and enrichment of overlapping down-regulated genes between pre-starter and starter pig’s uterus. Supp Table S3-5. MGI phenotypes and Human diseases of genes (UP and DOWN) enriched by GO enrichment in pre-starter pig’s uterus. Supp Table S3-6. KEGG pathway enrichment of DEGs between Ctrl and ZEN treatment group in pre-starter pig’s uterus, thymus, spleen, liver and inguinal lymph nodes. Supp Table S3-7. KEGG pathway enrichment of DEGs between Ctrl and ZEN treatment group in starter pig’s uterus, thymus, spleen, liver and inguinal lymph nodes. Supp Table S3-8. List of DEGs involving immune diseases & system on the top 30 KEGG pathways in pre-starter and starter pig’s uterus. Supp Table S3-9. List of DEGs enriched in each overlapping KEGG pathways (top 30) between pre-starter and starter pig’s thymus, spleen, liver and inguinal lymph nodes. Supp Table S3-10. KEGG pathway enrichment of overlapping up-regulated genes in pre-starter and starter pig’s uterus. Supp Table S3-11. KEGG pathway enrichment of overlapping down-regulated genes in pre-starter and starter pig’s uterus. Supp Table S3-12. GO enrichment of DEGs between Ctrl and ZEN treatment group in pre-starter and starter pig’s uterus. Supp Table S3-13. List of genes for expression pattern analysis in starter pig’s uterus and thymus. Supp Table S3-14. KEGG pathway enrichment of genes enriched in profile 2 of expression pattern analysis in starter pig’s uterus and thymus. Supp Table S3-15. GO enrichment of genes enriched in profile 2 of expression pattern analysis in starter pig’s uterus and thymus. Supp Table S3-16. GO enrichment of up-regulated and down-regulated genes between Ctrl and ZEN treatment group in starter pig’s ovary. Supp Table S3-17. GO classification and enrichment of DEGs between Ctrl and ZEN treatment group in starter pig’s overy.

附加文件4：补充表S3-1：对照组（control, Ctrl）与玉米赤霉烯酮（zearalenone, ZEN）处理组哺乳前期仔猪子宫、胸腺、脾脏、肝脏及腹股沟淋巴结的差异表达基因（differentially expressed genes, DEGs）列表。补充表S3-2：对照组与玉米赤霉烯酮处理组育成仔猪子宫、胸腺、脾脏、肝脏、腹股沟淋巴结及卵巢的差异表达基因列表。补充表S3-3：哺乳前期仔猪与育成仔猪子宫重叠上调基因的基因本体（Gene Ontology, GO）分类与富集分析结果。补充表S3-4：哺乳前期仔猪与育成仔猪子宫重叠下调基因的GO分类与富集分析结果。补充表S3-5：哺乳前期仔猪子宫GO富集分析所富集基因的小鼠基因组信息学（Mouse Genome Informatics, MGI）表型及人类疾病关联信息。补充表S3-6：对照组与玉米赤霉烯酮处理组哺乳前期仔猪子宫、胸腺、脾脏、肝脏及腹股沟淋巴结差异表达基因的京都基因与基因组百科全书（Kyoto Encyclopedia of Genes and Genomes, KEGG）通路富集分析结果。补充表S3-7：对照组与玉米赤霉烯酮处理组育成仔猪子宫、胸腺、脾脏、肝脏及腹股沟淋巴结差异表达基因的KEGG通路富集分析结果。补充表S3-8：哺乳前期仔猪与育成仔猪子宫位列前30的KEGG通路中涉及免疫疾病与免疫系统的差异表达基因列表。补充表S3-9：哺乳前期仔猪与育成仔猪胸腺、脾脏、肝脏及腹股沟淋巴结重叠KEGG通路（前30条）中富集的差异表达基因列表。补充表S3-10：哺乳前期仔猪与育成仔猪子宫重叠上调基因的KEGG通路富集分析结果。补充表S3-11：哺乳前期仔猪与育成仔猪子宫重叠下调基因的KEGG通路富集分析结果。补充表S3-12：对照组与玉米赤霉烯酮处理组哺乳前期及育成仔猪子宫差异表达基因的GO富集分析结果。补充表S3-13：育成仔猪子宫与胸腺表达模式分析所用基因列表。补充表S3-14：育成仔猪子宫与胸腺表达模式分析中表达谱模块（profile）2富集基因的KEGG通路富集分析结果。补充表S3-15：育成仔猪子宫与胸腺表达模式分析中表达谱模块2富集基因的GO富集分析结果。补充表S3-16：对照组与玉米赤霉烯酮处理组育成仔猪卵巢差异表达基因的上调及下调基因GO富集分析结果。补充表S3-17：对照组与玉米赤霉烯酮处理组育成仔猪卵巢差异表达基因的GO分类与富集分析结果。