Small RNA-sequencing of FUS H517Q and healthy iPSC-derived motor neurons

We sought to investigate changes in expression levels of small RNAs including microRNAs in FUS H517Q and healthy motor neurons Motor neurons were differentiated from patient-derived FUS H517Q and healthy iPSCs, and harvested at day 30. We performed gene expression profiling analysis using data obtained from bulk small RNA-seq. Comparative gene expression profiling using small RNA-seq analysis of FUS H517Q and healthy motor neurons.