Additional file 4 of Sex-specific transcriptome differences in a middle-aged frailty cohort

Additional file 4. Significant, differentially expressed genes in FRAM vs FRAF. Ensembl ID, gene symbol, Log2 fold change, padj value, gene type, and associated GO biological processes are listed for each respective DEG. Gene type and GO biological processes were retrieved from Ensembl’s BioMart (Ensembl Genes 104, Ensembl human genome version GRCh38.p13) as of August 10th, 2021. Information on whether genes were uniquely identified in the FRAM vs FRAF comparison group is provided in the column “Unique to FRAM vs FRAF”. For genes designated as “YES” in the “Unique to FRAM vs FRAF” column, information on whether they were previously identified in aging and/or frailty studies are provided in the column “Previously identified in aging and/or frailty studies”. References for previously identified genes are listed in the “References” column. “N/A” = information not available.

附加文件4：FRAM与FRAF组间的显著差异表达基因。本文件为每个差异表达基因（Differentially Expressed Genes, DEG）列出了Ensembl标识符（Ensembl ID）、基因符号（gene symbol）、log2倍变化值（Log2 fold change）、padj值、基因类型以及相关GO生物过程（Gene Ontology Biological Process）。基因类型与GO生物过程信息检索自Ensembl的BioMart数据库，数据截止至2021年8月10日，对应版本为Ensembl Genes 104、人类参考基因组版本GRCh38.p13。基因是否为FRAM与FRAF比较组所特有的相关信息，将在「FRAM与FRAF特有」列中提供。对于「FRAM与FRAF特有」列标注为"YES"的基因，其是否曾在衰老和/或衰弱相关研究中被鉴定的相关信息，将在「衰老和/或衰弱研究中已鉴定基因」列中提供。已鉴定基因的参考文献将列于「参考文献」列中。"N/A"代表相关信息不可用。