1.65 A resolution structure of SARS-CoV 3CL protease in complex with inhibitor 7j
收藏Protein Data Bank Japan2024-10-09 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/6w2a
下载链接
链接失效反馈官方服务：
资源简介：
1.65 A resolution structure of SARS-CoV 3CL protease in complex with inhibitor 7j Descriptor: (1S,2S)-2-[(N-{[(4,4-difluorocyclohexyl)methoxy]carbonyl}-L-leucyl)amino]-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, Replicase polyprotein 1a, [4,4-bis(fluoranyl)cyclohexyl]methyl ~{N}-[(2~{S})-1-[[(1~{R},2~{S})-1-[bis(oxidanyl)-oxidanylidene-$l^{5}-sulfanyl]-1-oxidanyl-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]carbamate Authors: Kashipathy, M.M, Lovell, S, Battaile, K.P, Rathnayake, A.D, Zheng, J, Kim, Y, Nguyen, H.N, Chang, K.O, Groutas, W.C. Deposit date: 2020-03-05 Release date: 2020-08-12 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.65 Å) Cite: 3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice. Sci Transl Med, 12, 2020
创建时间：
2020-03-05
