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OBOC Small-Molecule Combinatorial Library Encoded by Halogenated Mass-Tags

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https://figshare.com/articles/dataset/OBOC_Small_Molecule_Combinatorial_Library_Encoded_by_Halogenated_Mass_Tags/3320842
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资源简介:
A bromine-/chlorine-containing mass-tag encoding strategy for a small-molecule OBOC combinatorial library is reported. The resulting MALDI FTMS isotope pattern of each tag clearly defines the component building blocks of each “hit” bead in an 1890-member demonstration library screened on-bead for binding against streptavidin via both enzyme-linked colorimetric and Quantum Dot/COPAS assays.
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2004-10-14
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