Umeå SIMSAM Lab: A register-based research program connecting childhood with lifelong health and welfare

The Umea ̊ SIMSAM Lab in a nutshell:

1) The Lab was established for interdisciplinary research from childhood into lifelong health and welfare. It provides individual-level data on an entire nation’s population, covering demography, socioeconomics and health, otherwise rarely accessible to the re- search community.

2) Initiated in 2008 and launched in 2014, the Lab hosts comprehensive prospectively collected individual-level data on all 14.9 million individuals in Sweden between 1960 and 2010, including intergenerational links and geographical coordinates. The foundation is data from national registers at Statistics Sweden, rich in demography and socioeconomics. Health data come from national registers such as the Medical Birth Register, the Patient Register, the Prescribed Drug Register and the Celiac Disease Register. Regionally data have been enriched by systematic and long-term initiatives involving data collection on weight/height, lifestyle habits, self-rated health, injuries etc. Each person has a unique serial number that allows linkage on individual level from all data sources.

3) The combination of longitudinal and individual-level demographic, socioeconomic and health data provides unprecedented research opportunities. In addition, social relations within family, workplace and neighbourhood can be depicted as intergenerational links, and geographical coordinates are available.

4) Researchers are welcomed to make contact for collaborative projects. Contact information and details on data access are also available on: [www.simsam.org.umu.se].

Purpose:

We aim:
(1) to increase knowledge of social and environmental factors that are of importance to health and welfare during childhood and life as it continues, e.g. regarding family changes, exchanges between generations and geographical mobility.
(2) to increase knowledge of several childhood diseases (and injuries) considering the contribution of the social and economic context
(3) i) monitor the health and lifestyle of children from foetal life to adolescence, and identify any changes over time; ii) perform aetiological studies to increase the understanding of child-health determinants from a family and neighbourhood perspective; and iii) evaluate the Salut programme with respect to any changes in lifestyle, health and educational outcomes in the short and long term.
(4) to develop modern statistical methods for microdata research, primarily in order to perform aetiological studies with a life course perspective, and to assess complex interventions.

于默奥SIMSAM实验室（Umeå SIMSAM Lab）简介：

1) 本实验室旨在开展覆盖儿童时期至终生健康与福祉领域的跨学科研究，面向全国家庭人口提供个体层面数据，涵盖人口统计学、社会经济学与健康相关维度，此类数据此前极少向科研群体开放。

2) 本实验室于2008年启动筹备、2014年正式上线，托管了1960年至2010年间瑞典全部1490万人口的前瞻性个体层面综合数据集，包含代际关联与地理坐标信息。数据基础源自瑞典统计局（Statistics Sweden）的国家级登记库，涵盖丰富的人口统计学与社会经济学信息；健康数据则来自医疗出生登记册（Medical Birth Register）、患者登记册（Patient Register）、处方药登记册（Prescribed Drug Register）以及乳糜泻登记册（Celiac Disease Register）等国家级登记系统。区域数据通过系统性长期项目得到扩充，采集内容包括体重/身高、生活习惯、自评健康状况、损伤情况等维度。所有个体均拥有唯一序列号，可实现不同数据源间的个体层级关联。

3) 纵向追踪与个体层面的人口、社会经济及健康数据的有机结合，为科研工作提供了前所未有的机遇。此外，家庭、职场与社区内的社会关系可通过代际关联进行刻画，同时可获取地理坐标信息。

4) 欢迎科研人员联系洽谈合作项目。有关联系方式与数据获取的详细信息可访问：[www.simsam.org.umu.se]。

研究目标：
(1) 深化对儿童时期及终生健康与福祉相关社会与环境因素的认知，例如家庭结构变化、代际互动与地理迁移等议题；
(2) 结合社会与经济背景的影响，提升对多种儿童疾病（及损伤）的认知水平；
(3) ① 监测从胎儿期到青春期的儿童健康与生活方式状况，并识别其随时间的变化趋势；② 开展病因学研究，从家庭与社区视角加深对儿童健康决定因素的理解；③ 从短期与长期维度评估Salut项目在生活方式、健康状况与教育成果方面的变化情况；
(4) 研发面向微数据研究的现代统计方法，主要用于开展生命历程视角下的病因学研究，以及评估复杂干预措施。