Cortical regions showing effective connectivity with the striatum that was modulated by medication.

Regions showing effective connectivity each striatal seed are displayed in Figure 6. Brodmann areas were defined by the Talairach and Tournoux atlas. Coordinates represent distance in mm from anterior commissure: x, right(+)/left (−); y, anterior (+)/posterior (−); z, superior (+)/inferior (−). B  =  bilateral hemispheres; L  =  left hemisphere; R  =  right hemisphere; SMA  =  supramarginal gyrus.
1The correlation between a basal ganglia seed and a cortical region was typically greater OFF than ON medication. An exception was the correlation between the left putamen and the left superior/middle frontal cortex (BA 6), which was greater ON than OFF medication.