A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of BIIB074 in Subjects With Neuropathic Pain From Lumbosacral Radiculopathy

The primary objective of the study is to evaluate the efficacy of two dose regimens of
BIIB074 on neuropathic pain in participants with pain from lumbosacral radiculopathy (PLSR).
Secondary objectives are to evaluate the efficacy of 2 dose regimens of BIIB074 on additional
neuropathic pain measures and assessments of low back pain, disability, and quality of life;
To investigate the safety and tolerability of 2 dose regimens of BIIB074 and To characterize
the pharmacokinetics (PK) of BIIB074 in this population.