Upstream network analysis of HNF4A.

Figshare2021-10-01 更新2026-04-28 收录

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Upstream network analysis of HNF4A.

创建时间：

2021-10-01

Upstream network analysis of HNF4A.

NIAID Data Ecosystem10

Characterization of genome-wide DNA binding rhythms of HNF4A. Characterization of genome-wide DNA binding rhythms of HNF4A

HNF4A mRNA cycles over the coure of 24 h. To understand whether the chromatin binding of the transcription factor is also rhythmic, we performed ChIP-seq for HNF4A using mouse liver samples of ZT4 and

NIAID Data Ecosystem10

HNF4A

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

NIAID Data Ecosystem00

HNF4A. HNF4A

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem30

Molecular basis for autosomal-dominant renal Fanconi syndrome caused by HNF4A. Molecular basis for autosomal-dominant renal Fanconi syndrome caused by HNF4A

A specific missense mutation in the DNA binding domain of HNF4A, R85W, causes Fanconi renotubular syndrome (FRTS). To confirm results found in Drosophila, a direct reprogramming approach was applied.

NIAID Data Ecosystem10