Database used for evaluation of SALSA

This dataset consists of a subset of the ADNI database (http://adni.loni.usc.edu/), including 17 FLAIR scans with Alzheimer disease, acquired by a Siemens MAGNETOM Trio 3T scanner with the voxel size of 0.85×0.85×5.0 mm, changeable echo time (TE) of 149.42 ms, inversion time (TI) of 2250 ms, repetition time (TR) of 11002 ms, flip angle of 90°, and resolution of 256×256×42. It was used to evaluate our new method, called SALSA, for segmentation of white-matter hyperintensity lesions.This dataset consists of six archive files:"01_Source Images.zip" includes 17 source FLAIR images in the NIFTI format.<br>"02_Ground Thruth" includes 17 MAT files saved in the MATLAB environment. Each file includes a 3D binary image which determines hyperintensity voxels in the corresponding source image according to the expert delineation."03_Preprocessing Results" includes the 3D subject images after performing the preprocessing steps including rigid and non-rigid regisrations and bias correction."04_Probability Map of Skull" includes the probability maps of the skull for each subject image determined by the segmentation step."05_Probability Map of WM" includes the probability maps of the white matter for each subject image determined by the segmentation step."06_FLAIR Atlas" includes the source FLAIR atlas (GG.nii) and its processed version (RT_GG.nii) given by registration with the ICBM152 template.<br>

本数据集源自阿尔茨海默病神经成像计划（ADNI，Alzheimer's Disease Neuroimaging Initiative）数据库的子集，数据来源网址为http://adni.loni.usc.edu/。该数据集包含17例阿尔茨海默病患者的液体衰减反转恢复（FLAIR）扫描图像，由西门子MAGNETOM Trio 3T磁共振扫描仪采集。扫描参数如下：体素尺寸为0.85×0.85×5.0 mm，回波时间（TE）为149.42 ms，反转时间（TI）为2250 ms，重复时间（TR）为11002 ms，翻转角为90°，图像分辨率为256×256×42。本数据集用于评估我们提出的用于白质高信号病变分割的新型方法SALSA。
本数据集包含6个压缩归档文件：
1. "01_Source Images.zip"：内含17份NIFTI格式的原始FLAIR图像。
2. "02_Ground Truth"：内含17份MATLAB环境下保存的MAT格式金标准标注文件，每份文件对应一幅三维二值图像，用于根据专家标注确定对应原始图像中的高信号体素。
3. "03_Preprocessing Results"：内含经过预处理步骤后的受试者三维图像，预处理包括刚性配准、非刚性配准以及偏置场校正。
4. "04_Probability Map of Skull"：内含通过分割步骤得到的各受试者图像的颅骨概率分布图。
5. "05_Probability Map of WM"：内含通过分割步骤得到的各受试者图像的白质概率分布图。
6. "06_FLAIR Atlas"：内含经ICBM152模板配准得到的原始FLAIR标准脑图谱（GG.nii）及其处理后的版本（RT_GG.nii）。