Participant characteristics OVG2014/01(PATCH) study.
收藏Figshare2020-10-20 更新2026-04-28 收录
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ST-ST Re-Challenge = Homologous re-challenge with S. Typhi following previous S. Typhi challenge. SPT-SPT Re-Challenge = Homologous re-challenge with S. Paratyphi following previous S. Paratyphi challenge. ST-SPT Re-Challenge = Heterologous re-challenge with S. Paratyphi following previous S. Typhi challenge. SPT-ST Re-Challenge = Heterologous re-challenge with S. Typhi following previous S. Typhi challenge. Prior known typhoid vaccination of any type was an exclusion criterion for enrolment into the naïve arm of the study. Participants with prior history of Vi-polysaccharide vaccination were eligible for enrolment in previous paratyphoid challenge studies. Participants with a history of Vi-polysaccharide, Vi-tetanus toxoid conjugate, Ty21a, M01ZH09 vaccination received either vaccine as part of previous human challenge studies assessing vaccine efficacy. [21, 22] Minimum interval between primary challenge and re-challenge was 12 months.
创建时间：
2020-10-20
