Additional file 2 of DNA 5-hydroxymethylcytosine in pediatric central nervous system tumors may impact tumor classification and is a positive prognostic marker

Additional file 2. Gene List: List of genes with a high proportion of represented probes being hyperhydroxymethylated. Gene name, number of probes for each gene represented in the EPIC array, number of probes that qualified as high 5hmC and the calculated percentage. Results of GREAT analysis: Results of submitting the coordinates of the high 5hmC loci to Genomic Regions Enrichment of Annotations Tool (GREAT) analysis. Terms associated with biologic process, cellular components and molecular function are included as well as P value and FDR Q-Values.

附加文件2. 基因列表：收录了高比例代表性探针呈高羟甲基化状态的基因。列表包含基因名称、各基因在EPIC阵列中的代表性探针数目、符合高5-羟甲基胞嘧啶（5hmC）判定标准的探针数目，以及计算得到的占比。
GREAT分析结果：将高5hmC位点的基因组坐标提交至基因组区域注释富集工具（Genomic Regions Enrichment of Annotations Tool, GREAT）开展分析所得的结果。该结果涵盖了与生物过程、细胞组分及分子功能相关的富集术语，同时包含P值与FDR Q值。