The Total Synthesis of (+)-Hapalindole Q by an Organomediated Diels−Alder Reaction
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https://figshare.com/articles/dataset/The_Total_Synthesis_of_Hapalindole_Q_by_an_Organomediated_Diels_Alder_Reaction/3359296
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资源简介：
The total synthesis of (+)-hapalindole Q has been achieved. The key step is a Diels−Alder
reaction mediated by MacMillan's organocatalyst to provide the critical intermediate with high enantioselectivity (93% ee). This step establishes the proper arrangement of the required four contiguous
stereocenters, including the quaternary center, and represents the first successful application of an
enantioselective organomediated Diels−Alder reaction in total synthesis.
创建时间：
2016-05-07
