Malignant neoplasm of testis - Male, 27 - Tissue image [6080730009646291]

This is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 27Clinical description: Tumour of the left testicleGender: MaleDiagnosis:Classification: ICD-10_10-20Classification code: Chapter II - NeoplasmsDiagnosis: Malignant neoplasm of testisResult of the histopathological examination: Mixed testicular germ cell tumor, which includes seminoma, germ cell carcinoma and yolk sac tumor. Diffuse intratubular germ cell neoplasia in the adjacent parenchyma. Seminoma accounts for approximately 60% of malignant uterus, 35% of germ cell carcinoma and 5% of yolk sac tumour. Germ cell carcinoma with areas of extensive necrosis (about 70-80% of its tissue).
The seminoma focally infiltrates the testicle network. The tumor is confined to the testicle parenchyma and does not infiltrate the lining.
Vascular invasion has not been identified.
IHC: seminoma-OCT 3/4 (+), germ cell carcinoma -OCT 3/4 (+), CD 30 (+), beta HCG (-), Glipican 3 (-), AFP (-), yolk sac tumor -AFP (+), Glipican 3 (+).Sample:Material: FFPECollecting method: Surgical specimenTopography: MALE GENITAL ORGANSOrgan: TESTISTissue: Testis, NOSType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk

本数据集包含格但斯克医科大学（Medical University Gdańsk）获取并存储于ZMDL-GUMED的睾丸组织样本病理组织学图像。该样本图像采用Pannoramic 250 3DHistech玻片扫描仪以20倍放大倍率采集，保存为DICOM格式。

患者、样本及诊断的详细信息如下：
患者：年龄27岁；性别：男性；临床描述：左侧睾丸肿瘤；
诊断分类：ICD-10_10-20分类，分类编码为第二章——肿瘤；诊断：睾丸恶性肿瘤；
组织病理学检查结果：混合性睾丸生殖细胞肿瘤，包含精原细胞瘤（seminoma）、生殖细胞癌（germ cell carcinoma）与卵黄囊瘤（yolk sac tumor）；邻近实质内可见弥漫性曲细精管内生殖细胞肿瘤变。其中精原细胞瘤约占恶性子宫肿瘤的60%、生殖细胞癌的35%以及卵黄囊瘤的5%。生殖细胞癌伴大范围坏死区域（约占其组织总量的70%~80%）。
精原细胞瘤局灶性浸润睾丸网。肿瘤局限于睾丸实质内，未侵犯被膜。未检测到血管浸润。

免疫组化（Immunohistochemistry, IHC）结果：精原细胞瘤-OCT 3/4（阳性），生殖细胞癌-OCT 3/4（阳性）、CD30（阳性）、β-绒毛膜促性腺激素（β-human chorionic gonadotropin, β-HCG）（阴性）、磷脂酰肌醇蛋白聚糖3（Glypican 3）（阴性）、甲胎蛋白（Alpha-Fetoprotein, AFP）（阴性）；卵黄囊瘤-AFP（阳性）、Glypican 3（阳性）。

样本相关信息：
样本材料：福尔马林固定石蜡包埋（Formalin-Fixed Paraffin-Embedded, FFPE）；采集方式：手术标本；
部位：男性生殖器官；器官：睾丸；组织：睾丸，未特指类型；
染色类型：阳性/HE染色；不适用；抗体：未使用；

成像技术参数：
设备：Pannoramic 250 3DHistech；镜头放大倍数：20×；
数据来源：格但斯克医科大学。