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Epigenomic Profiling of Primary Gastric Adenocarcinoma Reveals Super-enhancer Heterogeneity [RNA-seq]

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NIAID Data Ecosystem2026-05-02 收录
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Regulatory elements in cancer remain poorly characterized in primary solid tumors. Here we applied microscale histone modification profiling to delineate the landscape of somatic promoters and super-enhancers in primary gastric adenocarcinoma, analyzing 94 epigenomic profiles of primary tumors, normal tissues, and cell lines Total RNA extracted from gastric cell lines, tumors and matched gastric non-malignant (normal) tissues was sequenced.

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2024-09-23
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