Children's Report of Parental Behavior Inventory (CRPBI)

YOUth is a large-scale longitudinal cohort study following children from the city of Utrecht and its surrounding areas in their development from pregnancy until early adulthood. The YOUth cohort focuses on neurocognitive development involved in two core characteristics of behavioral development: social competence and behavioral control. YOUth includes children from the general population to cover the whole range of variation in behavioral development, ranging from uncomplicated development, through problem behavior, to psychiatric disorders. To understand why some children develop problematic behavior, and others show resilience, YOUth measures a broad range of biological, child-related and environmental determinants.

YOUth conducts repeated measurements at regular intervals (i.e. 'waves'). Specifically, the study has two inclusion moments: YOUth Baby & Child and YOUth Child & Adolescent. YOUth applies a flexible longitudinal design to the cohorts, meaning that children are measured at broader age ranges (3-year age ranges) at each wave. The main benefit of the flexible age design is that it provides more detailed information on the neurodevelopmental curves over time.

An extensive data set is generated, including 3D-ultrasound sweeps of the fetal brain, eye tracking, EEG, (f)MRI, computer tasks, cognitive measurements and parent-child observations. We also collect a broad range of questionnaires on behavior, personality, health, lifestyle, parenting, child development, use of (social) media and more. Finally, (umbilical) blood samples, buccal swabs, saliva and hair samples are collected at each visit, and stored in the UMC Utrecht Biobank.

YOUth是一项大型纵向队列研究，追踪乌得勒支市及其周边地区儿童从妊娠阶段直至成年早期的发育历程。该队列聚焦于行为发展两大核心特征所关联的神经认知发育：社交能力与行为控制。YOUth研究纳入普通人群中的儿童，以覆盖行为发展的全部变异谱系，从无并发症的正常发育、问题行为直至精神障碍。为探明部分儿童出现问题行为的成因，以及另一部分儿童展现出韧性的机制，YOUth研究测量了涵盖生物学、儿童自身相关及环境性在内的多类决定因素。
YOUth研究按照固定间隔开展重复测量（即“评估波次”）。具体而言，该研究设有两个入组阶段：YOUth婴儿与儿童队列（YOUth Baby & Child）以及YOUth儿童与青少年队列（YOUth Child & Adolescent）。该研究为队列采用了灵活的纵向研究设计，即每个评估波次针对的儿童年龄跨度为3年区间。这种灵活的年龄设计核心优势在于，可为随时间推移的神经发育曲线提供更为精细的信息。
该研究生成了大规模综合数据集，涵盖胎儿脑部三维超声扫描、眼动追踪、脑电图（EEG）、功能磁共振成像（fMRI）、计算机认知任务、神经认知测评以及亲子互动观察等多类数据。此外，研究团队还收集了涵盖行为、人格、健康、生活方式、养育方式、儿童发育、社交媒体使用等在内的大量问卷数据。最后，每次访视都会采集脐带血、口腔拭子、唾液及毛发样本，并存储于乌得勒支大学医学中心（UMC Utrecht）生物样本库。