Crystal structure of BACE1 complexed with an inhibitor
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Crystal structure of BACE1 complexed with an inhibitor Descriptor: Beta-secretase 1, CHLORIDE ION, N-[(1S,2R)-1-BENZYL-3-(CYCLOPROPYLAMINO)-2-HYDROXYPROPYL]-5-[METHYL(METHYLSULFONYL)AMINO]-N'-[(1R)-1-PHENYLETHYL]ISOPHTHALAMIDE, ... Authors: Xu, Y.C, Li, M.J, Greenblatt, H, Chen, T.T, Silman, I, Sussman, J.L. Deposit date: 2011-09-08 Release date: 2011-11-23 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations Acta Crystallogr.,Sect.D, 68, 2012
创建时间:
2011-09-08



