SMNDC1 links chromatin remodeling and splicing to regulate pancreatic hormone expression [ATAC-seq]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE201246
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资源简介：
We have found that loss of SMNDC1 (Survival Motor Neuron Domain Containing 1), a component of the spliceosome complex, in both murine alpha cells and human islets is capable of inducing an overall increase in beta cell markers and activating insulin transcription. ATAC-seqs in alphaTC1 cells (murine alpha cell line) 5 days after transduction with either an Smndc1 or Atrx-targeting shRNA.
创建时间：
2022-07-03
