Expression data from WT and TREM2 deficient microglia in a mouse model of Alzheimer's disease

ChEBI2015-03-13 更新2026-07-21 收录

阿尔茨海默病机制

胶质细胞基因表达分析

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Expression data from WT and TREM2 deficient microglia in a mouse model of Alzheimer's disease

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2015-03-13

Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and -independent cellular responses in Alzheimer's disease [7 months]

阿尔茨海默病机制

转录组测序

Glia have been implicated in Alzheimer's disease (AD) pathogenesis. Variants of the microglia receptor TREM2 increase AD risk and activation of âdisease-associated microgliaâ (DAM) is dependent on

NIAID Data Ecosystem50

Table_1_Benign Regulation of the Astrocytic Phospholipase A2-Arachidonic Acid Pathway: The Underlying Mechanism of the Beneficial Effects of Manual Acupuncture on CBF.DOC

阿尔茨海默病机制

针刺调控脑血流

BackgroundThe astrocytic phospholipase A2 (PLA2)-arachidonic acid (AA) pathway is crucial in understanding the reduction of cerebral blood flow (CBF) prior to cognitive deterioration. In complementary

NIAID Data Ecosystem10

Data Sheet 1_Western diet-induced visceral adipose tissue inflammation promotes Alzheimer’s disease pathology via microglial activation in a mouse model.docx

阿尔茨海默病机制

饮食诱导神经炎症

IntroductionWestern diet (WD)-induced visceral adipose tissue (VAT) inflammation is characterized by adipocyte hypertrophy, hypoxia, and apoptosis. Epididymal white adipose tissue (eWAT), a representa

NIAID Data Ecosystem00

The cryo-EM structure of AV-45 bound type3 amyloid beta 42 fibril.

蛋白质结构解析

阿尔茨海默病机制

The cryo-EM structure of AV-45 bound type3 amyloid beta 42 fibril. Descriptor: P3(40) Authors: Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D. Deposit date: 2023-08-15 Release date: 2024-08-21 Last modified: 2025

Protein Data Bank Japan2025-07-02 更新20

Exercise alleviates cognitive dysfunction in Alzheimer's disease mice via skeletal muscle-derived extracellular vesicles which enhance plaque clearance by microglia [RNA-Seq]

阿尔茨海默病机制

胶质细胞功能调控

Exercise confers cognitive benefits in Alzheimer's disease (AD), yet the underlying mechanisms remain incompletely understood. The skeletal muscle functions as an endocrine organ that secretes myokine

NIAID Data Ecosystem00

Expression data from WT and TREM2 deficient microglia in a mouse model of Alzheimer's disease

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