Autocatalytic activation of MMP3

After the initial cleavage of the N-terminus, MMP3 undergoes autocatalysis and cleavage of the His99-Phe100 bond (Nagase et al. 1990, 1991). Residue numbering given here is based on the UniProt canonical sequence.在N端切割的初步完成后，MMP3经历自催化作用及His99-Phe100键的切割（Nagase等，1990，1991）。此处给出的残基编号基于UniProt的规范序列。