Effects of SB216763 on the nuclear export of the AR.

Western blots were performed as described under Figure 3. Nuclear AR levels were determined by densitometry normalized to the corresponding lamin levels (loading control). Nuclear AR levels are expressed in AR/lamin of corresponding controls grown in absence of DHT and SB216763 ( = 100%). Each value represents the mean of 3 independent experiments ± standard deviation (p-values compared to corresponding untreated controls:*p = 0.016;**p = 0.009;***p = 0.001; p-values compared to corresponding DHT treated controls:#p = 0.055;##p = 0.019;###p = 0.009).