five

DDQ-Mediated Three-Component Dioxygenation of Alkenes

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NIAID Data Ecosystem2026-03-09 收录
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https://figshare.com/articles/dataset/DDQ-Mediated_Three-Component_Dioxygenation_of_Alkenes/3850266
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A new DDQ-mediated three-component dioxygenation of alkenes has been established, providing a direct and metal-free access toward densely functionalized 4,5-dichloro-3-hydroxyphthalonitrile derivatives with generally good to excellent yields under mild conditions. During this process, DDQ plays dual roles as both a dehydrogenation reagent and a coupling partner, enabling oxidative coupling to form two C–O functionalities in a highly atom-economy fashion.
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2016-10-03
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