TALEN-based knockout of mir-141 and mir-200c in SK-BR-3 cells
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下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP030475
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资源简介：
We used transcription activator-like effector nucleases (TALENs) to generate knockout cells for two related microRNAs (miRNAs), mir-141 and mir-200c, which belong to the deeply conserved mir-200 family. By carrying out deep sequencing, we identified the target genes of each miRNA. Interestingly, miR-141 and miR-200c, despite their overall similarity, suppressed largely non-overlapping groups of targets. Overall design: Analysis of global mRNA level change in mir-141 and mir-200c knockout compared to wild type cells
创建时间：
2019-09-23
