New technique of intragastric sleeve: viability and survival in a pig model

Abstract Developing a less invasive, practical and cost-effective operative technique for obesity treatment represents a pressing need for our society. In this way, intragastric single port sleeve by endoplication was tested in six pigs during 18 weeks. Celiotomy was performed with animal placed in dorsal decubitus position. Single port gastrostomy was performed and double tobacco pouch sutures were made in fundic region, making a gastric sleeve. At the end, stomach layers and skin were closed in a conventional manner. Means and the standard deviations of surgical time were calculated. The procedure was simple and all animals survived; there were no significant blood loss and no intra and postoperative complications. The procedure was fast (67.4 minutes). The technique has the advantage of not requiring the use of mechanical sutures, making it less costly. The innovation of this procedure was the use of a single port gastrostomy device to perform an intraluminal sleeve. What made this technique less invasive were the use of a single port, nonmanipulation of the stomach intra-abdominally, ease of execution and no need of pneumoperitoneum. The new technique is acceptable and has reproducible viability, had a short procedure time without intra and postoperative complications.

摘要：开发一种微创、实用且经济高效的肥胖症治疗手术技术，是当前社会的迫切需求。本研究针对经腔内缝合的胃内单端口袖状成形术，在18周的试验周期内对6头猪开展了相关实验。实验动物取背卧位实施剖腹术，先行单端口胃造口术，随后在胃底区域进行双荷包缝合以构建袖状胃结构。术毕，按常规方式缝合胃壁各层与皮肤切口。研究人员计算了手术时长的平均值与标准差。结果表明，该术式操作简便，所有实验动物均存活，未出现显著失血量，亦无术中及术后并发症；手术耗时较短，平均时长为67.4分钟。该技术无需使用机械缝合器械，因而具备成本优势。本术式的创新之处在于采用单端口胃造口器械完成腔内袖状成形。其微创性体现在：仅使用单端口、无需腹腔内操作胃部、操作简便且无需建立气腹。该新型术式临床可接受且可重复性强，手术耗时短且无术中及术后并发症。