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MiRNA expression in a patient-derived CRC model after treatment with TGFB1

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE233234
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We determined the miRNA expression changes upon activation and inactivation of the TGFB signaling cascade We treated a patient-derived CRC spheroid model with recombinant TGFB1 or a vehicle control for 7 days, and let them recover for additional 7 days in the absence of TGFB1. Here, we analyzed the miRNA expression pattern by small RNA sequencing and determined miRNAs expression in all conditions.
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2023-11-02
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