MOESM5 of Live and inactivated Salmonella enterica serovar Typhimurium stimulate similar but distinct transcriptome profiles in bovine macrophages and dendritic cells

Additional file 5. An Excel sheet listing the genes forming a common transcriptional response in DC and Mø in response to live and inactivated S. Typhimurium (FDR ≤ 5%, fold change ≥ 1.8). The average fold changes compared to unstimulated cells are listed for each sample set; DC infected with live S. Typhimurium (DC_L), DC stimulated with inactivated S. Typhimurium (DC_D), Mø infected with live S. Typhimurium (Mø_L) and Mø stimulated with inactivated S. Typhimurium (Mø_D). Genes shown in bold are represented by more than one probe-set and the average fold change across the probe-sets is listed. Where possible the HGNC gene names and symbols have been used. The list includes five unannotated transcripts and their position on the bovine genome relative to neighbouring genes is described. Fold changes in red highlight where the fold change in DC and/or Mø is more than 1.5-fold different in response to live and inactivated S. Typhimurium.

附加文件5：本Excel表格收录了树突状细胞（Dendritic Cell, DC）与巨噬细胞（Macrophage, Mø）在感染或经灭活鼠伤寒沙门氏菌（Salmonella Typhimurium, S. Typhimurium）刺激后，共同产生转录应答的基因，筛选阈值为错误发现率（False Discovery Rate, FDR）≤5%，倍数变化（fold change, FC）≥1.8。
表格列出了各样本组与未刺激细胞相比的平均倍数变化值，样本组包括：活鼠伤寒沙门氏菌感染树突状细胞组（DC_L）、灭活鼠伤寒沙门氏菌刺激树突状细胞组（DC_D）、活鼠伤寒沙门氏菌感染巨噬细胞组（Mø_L）以及灭活鼠伤寒沙门氏菌刺激巨噬细胞组（Mø_D）。
以粗体标注的基因对应多个探针集（probe-set），表格同时列出了这些探针集的平均倍数变化值。本表格尽可能采用人类基因命名委员会（HUGO Gene Nomenclature Committee, HGNC）的基因名称与符号进行标注。
该列表包含5条未注释转录本，并描述了它们在牛基因组中相对于邻近基因的位置。
以红色标注的倍数变化值，代表树突状细胞和/或巨噬细胞在活鼠伤寒沙门氏菌与灭活鼠伤寒沙门氏菌刺激下，两组处理间的倍数变化差值超过1.5倍的基因。