Data associated with "Fast and reliable quantitative measures of white matter development with magnetic resonance fingerprinting", Imaging Neuroscience, 2025

This dataset accompanies the publication "Fast and reliable quantitative measures of white matter development with magnetic resonance fingerprinting", published in Imaging Neuroscience, 2025. In this paper, we examine the reliability of an efficient quantitative multiparameter mapping method - Magnetic Resonance Fingerprinting (MRF) - in children scanned longitudinally. We examined the impact of scan time and B0 inhomogeneity correction on scan-rescan reliability of values in white matter, by comparing single 2-min and combined two 2-min scans, with and without B0-correction. Using diffusion tractography, we segmented major white matter fiber tracts and examined the profiles of MRF-derived T1 values along each tract. We found that T1 values from MRF showed similar or greater reliability compared with diffusion parameters. Lastly, we found that R1 (1/T1) values in multiple white matter tracts were significantly correlated with age. In sum, MRF-derived T1 values were highly reliable in a longitudinal sample of children and replicated known age effects. Reliability in white matter was improved by longer scan duration but was not affected by B0-correction, making it a quick and straightforward scan to collect. In this dataset we share the preprocessed diffusion scans as well as the MRF-derived T1 maps generated by the four reconstruction pipelines described in the manuscript. We further include a dataframe with diffusion and T1 metrics averaged across 21 white matter tracts.

本数据集配套发表于2025年《Imaging Neuroscience》的论文《基于磁共振指纹成像的白质发育快速可靠定量测量方法》（原标题："Fast and reliable quantitative measures of white matter development with magnetic resonance fingerprinting"）。本研究针对接受纵向扫描的儿童群体，评估了一种高效定量多参数成像方法——磁共振指纹成像（Magnetic Resonance Fingerprinting, MRF）的可靠性。我们通过对比单次2分钟扫描与两次各2分钟的合并扫描（分别施加与未施加B0不均匀性校正（B0 inhomogeneity correction）），探究了扫描时长与B0不均匀性校正对白质区域扫描-重扫描可靠性（scan-rescan reliability）的影响。借助扩散纤维束追踪（diffusion tractography）技术，我们对主要白质纤维束进行了分割，并分析了每条纤维束上MRF衍生T1值的分布特征。研究发现，MRF得到的T1值的可靠性与弥散参数相当甚至更优。此外，我们还发现多条白质纤维束内的R1（1/T1）值与年龄呈显著相关。综上，在儿童纵向扫描样本中，MRF衍生的T1值具有极高的可靠性，且复现了已报道的年龄相关效应。扫描时长的增加可提升白质区域的测量可靠性，但B0不均匀性校正对其无显著影响，这使得MRF扫描成为一种快速简便的数据采集方案。本数据集包含预处理后的弥散扫描数据，以及论文中所述四种重建流程生成的MRF衍生T1图谱。此外，我们还提供了一个数据框（dataframe），其中包含了21条白质纤维束的平均弥散指标与T1指标。