The p-values associated with the comparison of the RA and CTR groups and NARAC-A and NARAC-C using the successful models derived from pathways under consideration.

According to Bonferroni’s correction, a fitness p-value −9 and a randomization test p-value p-values of the models showing significant association with rheumatoid arthritis comparing RA vs. CTR are in bold. Of these 12 pathways, five were replicated in NARAC dataset at the significance level of 0.00208 and three were replicated at the significance level of 0.05. The p-values of these replicated models are also in bold.