Clinical and epidemiology evaluation of Aids-infected patients hospitalized between 2011 and 2016 in the Santos region of Brazil

Abstract INTRODUCTION: We assessed the clinical-epidemiological profile of acquired immune deficiency syndrome (AIDS) patients in the Santos region (São Paulo state) with the highest AIDS prevalence in Brazil. METHODS Information was extracted from records of 409 AIDS-infected patients hospitalized between 2011 and 2016. RESULTS: Human immunodeficiency virus (HIV) was diagnosed in 24.7% of patients during admission, and 39.6% of already diagnosed patients received highly active antiretroviral therapy (HAART) irregularly. The mortality rate was 19.1%, and the main secondary manifestations were neurotoxoplasmosis and tuberculosis. CONCLUSIONS: AIDS patients in the Santos region had high rates of late diagnosis and low treatment adherence.

引言：本研究评估了巴西艾滋病患病率最高的圣保罗州桑托斯地区获得性免疫缺陷综合征（acquired immune deficiency syndrome, AIDS）患者的临床流行病学特征。
研究方法：本研究提取了2011年至2016年间收治的409例艾滋病感染住院患者的病历资料。
研究结果：24.7%的患者在入院时首次确诊人类免疫缺陷病毒（human immunodeficiency virus, HIV）感染；已确诊患者中，39.6%未规律接受高效抗反转录病毒治疗（highly active antiretroviral therapy, HAART）。患者病死率为19.1%，主要继发并发症为神经弓形体病与结核病。
研究结论：桑托斯地区的艾滋病患者确诊偏晚比例较高，且治疗依从性较差。