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Krencik NPCs, iAstros, Chemogenetic iAstros, OptoNeurons

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE187436
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RNAseq for comparison of human pluripotent stem cell-derived neural subtypes containing genetic-encoded tools. The purpose of this study was to validate cellular identify of neural subtypes and to assess the consequence of Gq-based chemogenetic activation of astrocytes over time. All cells are from the same parental human pluripotent stem cell line (WT-C11) and all samples were extracted from cell cultured as a monolayer on matrigel in the same basal media formulation.
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2022-02-13
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