Electron-beam generated macroporous cryogels.

Polymeric cryogels represent a relatively new class of porous monolithic scaffolds. These sponge-like materials are characterized by an interconnected network of pores with diameters ranging from 10 - 200 μm. Due to their unique properties they are particularly suitable for biological application. The matrices presented in this paper are synthesized at sub-zero temperatures from gel-forming precursors by free radical polymerization. Thereby, the pores are shaped by ice-crystals. The main fields of application are in biotechnology, biomedicine, and tissue engineering. At the Leibniz Institute of Surface Modification a novel strategy to generate macroporous (biocompatible) cryogels was developed. The reaction is started by electrons of a high energy accelerator. No additional initiators are required. This short perspective highlights our recent achievements in the field of E-beam (electron beam) synthesis of macroporous cryogels.

聚合物冷冻凝胶（Polymeric cryogels）是一类相对新兴的多孔整体支架材料。这类海绵状材料的特征为拥有孔径范围介于10至200微米的连通孔隙网络。凭借其独特的性能，该类材料尤其适用于生物领域应用。本文所涉及的基质材料，通过自由基聚合反应，由成凝胶前驱体在亚零温环境下合成制得。在此过程中，孔隙由冰晶模板塑造而成。其主要应用领域涵盖生物技术、生物医学与组织工程。在莱布尼茨表面改性研究所（Leibniz Institute of Surface Modification），科研人员开发出了一种制备大孔径（生物相容性）冷冻凝胶的全新策略。该合成反应由高能加速器产生的电子引发，无需额外添加引发剂。本短综述概述了我们在大孔径冷冻凝胶的电子束（E-beam，electron beam）合成领域取得的最新研究进展。