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The important role of GPR84 in MLL leukemogenesis
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创建时间：
2014-10-15
相关数据集
Combined inhibition of transcriptional and IGF2BP3-driven post-transcriptional gene regulation in MLL-AF4 leukemogenesis
RNA binding proteins are emerging as a novel class of therapeutic targets in cancer, including in leukemia, given their important role in post-transcriptional gene regulation, and have the unexplored
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Functional interdependency of BRD4 and DOT1L in MLL leukaemia. Functional interdependency of BRD4 and DOT1L in MLL leukaemia
This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
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Msi2 sustains the MLL leukemia stem cell regulatory program. Mus musculus
Leukemia stem cells (LSCs) are found in most aggressive myeloid diseases and contribute to therapeutic resistance. Genetic and epigenetic alterations cause a dysregulated developmental program in leuk
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Msi2 sustains the MLL leukemia stem cell regulatory program
Leukemia stem cells (LSCs) are found in most aggressive myeloid diseases and contribute to therapeutic resistance. Genetic and epigenetic alterations cause a dysregulated developmental program in leuk
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Characterizing the Impact of MLL Fusion Variants and Fusion Partners on Leukemia Plasticity Using a Human CRISPR-Engineered MLL-Rearranged Leukemia Model
Acute leukemias involving MLL (KMT2A) rearrangements are aggressive hematologic malignancies associated with poor prognosis. MLL fusions typically involve MLL exons 8-14, with AF4 (AFF1) and AF9 (MLLT
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