Crystal structure of Neisseria meningitidis ClpP protease in complex with phosphine oxide compound ACP6-12
收藏Protein Data Bank Japan2024-09-25 更新2026-06-30 收录
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Crystal structure of Neisseria meningitidis ClpP protease in complex with phosphine oxide compound ACP6-12 Descriptor: 2-{bis[5-(trifluoromethyl)pyridin-2-yl]phosphoryl}-2-methyl-N-(2-{[2-(trifluoromethyl)phenyl]sulfanyl}ethyl)propanamide, ATP-dependent Clp protease proteolytic subunit Authors: Mabanglo, M.F, Houry, W.A. Deposit date: 2023-05-30 Release date: 2024-09-18 Last modified: 2024-09-25 Method: X-RAY DIFFRACTION (2.33 Å) Cite: Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for Antibiotics that Dysregulate Bacterial ClpP Proteases. J.Med.Chem., 67, 2024
创建时间：
2023-05-30
