Plasma cell myeloma - Female, 51 - Tissue image [6130730026848371]

This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 51Clinical description: No clinical data.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: PLASMA CELL TUMORSDiagnosis: Plasma cell myelomaResult of the histopathological examination: Myeloma: hypercellular bone marrow, diffuse and interstitial infiltration of atypical plasma cells (CD138+, kappa+, lambda-, Cd20-). Focally reticulin fibrosis (1+).Sample:Material: FFPECollecting method: Bone marrow biopsyTopography: HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMSOrgan: HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMSTissue: Bone marrowType of staining: positive/HEStaining: May Grunwald GiemsaAntibody: Not applicableTechnology:Equipment: Pannoramic 1000Lens: 20xOrganization:Source: Medical University Gdańsk

本数据集为格但斯克医科大学（Medical University Gdańsk）获取并存档于ZMDL-GUMED的造血与淋巴网状内皮系统（HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS）组织样本的组织病理图像。该样本图像采用Pannoramic 1000切片扫描仪（20倍放大倍率）采集，并以DICOM格式存储。

患者、样本与诊断详细信息如下：
1. 患者基本信息：年龄51岁，女性，无可用临床数据。
2. 诊断相关信息：依据ICD-O-3.2（ICD-O_3.2）分类标准，分类编码为浆细胞肿瘤（PLASMA CELL TUMORS），最终诊断为浆细胞骨髓瘤（Plasma cell myeloma）；组织病理学检查结果显示：骨髓瘤表现为骨髓增生极度活跃，非典型浆细胞呈弥漫性及间质性浸润（免疫表型：CD138阳性、kappa轻链阳性、lambda轻链阴性、CD20阴性），局灶性网状纤维纤维化（1+级）。
3. 样本参数：样本材料为福尔马林固定石蜡包埋（FFPE）组织，采集方式为骨髓活检，取材部位为造血与淋巴网状内皮系统，对应器官为造血与淋巴网状内皮系统，组织类型为骨髓。
4. 染色与成像细节：染色类型为阳性/苏木精-伊红（HE）染色，同时采用May Grunwald Giemsa染色；无需使用抗体标记；成像设备为Pannoramic 1000，镜头放大倍数为20倍，数据来源机构为格但斯克医科大学。