Crystal structure of human Mps1 (TTK) C604Y mutant in complex with NMS-P715
收藏Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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Crystal structure of human Mps1 (TTK) C604Y mutant in complex with NMS-P715 Descriptor: 1,2-ETHANEDIOL, Dual specificity protein kinase TTK, N-(2,6-DIETHYLPHENYL)-1-METHYL-8-({4-[(1-METHYLPIPERIDIN-4-YL)CARBAMOYL]-2-(TRIFLUOROMETHOXY)PHENYL}AMINO)-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE Authors: Hiruma, Y, Joosten, R.P, Perrakis, A. Deposit date: 2017-04-28 Release date: 2017-07-26 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures. J. Biol. Chem., 292, 2017
创建时间：
2017-04-28
