Transcriptional regulation of genes targeted by regulated miRNAs in c-Raf transgenic mice.

Given is the repression of target genes at the mRNA level in lung dysplasia [27] and lung adenocarcinoma [28]. The first column indicates the fold changes of genes repressed in lung dysplasia in c-Raf transgenic mice [27]. The second column indicates the fold changes of mRNAs repressed in lung adenocarcinomas from c-Raf mice. For each gene the percentage of immunohistochemistry signal intensity for lung tumors as compared to healthy surrounding tissue is given and is based on data reported in the Human Protein Atlas database. N/A = Non-Available data.