Aspects of images in magnetic resonance of liver tumors treated with transarterial selective internal radiotherapy with yttrium-90

ABSTRACT Transarterial selective internal radiation therapy with yttrium-90, also known as radioembolization, is a therapy based on the administration of resin or glass microspheres loaded with the radioisotope yttrium-90, via selective arterial catheterization of tumor-feeding vessels. It is classified as a type of locoregional therapy and its main goal is to treat patients with primary or secondary hepatic lesions that are unresectable and not responsive to other therapies. Since it is a new technology still restricted to very few hospitals in Brazil, but used in patients throughout the country, it is necessary to demonstrate the main aspects of hepatic lesions treated with selective internal radiation therapy found in magnetic resonance imaging, and to make specific considerations on interpretation of these images. The objective of this report is to demonstrate the main aspects of magnetic resonance imaging of unresectable primary or secondary hepatic lesions, in patients submitted to transarterial selective internal radiation therapy.

摘要：钇-90经动脉选择性内放射治疗（transarterial selective internal radiation therapy with yttrium-90），又称放射栓塞术（radioembolization），是一种通过对肿瘤供血血管实施选择性动脉插管，将装载有放射性同位素钇-90（yttrium-90）的树脂或玻璃微球注入体内的治疗方法。该疗法被归类为局部区域治疗手段，其核心目标是治疗无法手术切除且对其他疗法无响应的原发性或继发性肝脏病变患者。鉴于该项技术在巴西目前仍仅局限于极少数医院开展，但已在全国范围内的患者中得到应用，因此有必要阐明经选择性内放射治疗处理的肝脏病变在磁共振成像（magnetic resonance imaging, MRI）中的主要表现，并针对这类影像的解读要点进行专门说明。本报告旨在展示接受经动脉选择性内放射治疗的患者中，无法手术切除的原发性或继发性肝脏病变的磁共振成像主要特征。