Additional file 3: of DNA methylome-wide alterations associated with estrogen receptor-dependent effects of bisphenols in breast cancer

DNA methylome-wide results in biphenol-treated MCF-7 cells and in TCGA breast cancer patients. DNA methylome-wide results (DMPs and DMRs) of MCF-7 cells treated with BPA, BPF and BPS Âą ERI for 48â hrs and DNA methylome-wide results (DMPs) of ER-positive breast cancer tissues when compared to adjacent normal tissues in TCGA breast cancer patients. (XLSX 2.310 kb)

本数据集包含经双酚类物质处理的MCF-7细胞与癌症基因组图谱（The Cancer Genome Atlas, TCGA）乳腺癌患者的全基因组DNA甲基化组分析结果。具体包括：经双酚A（Bisphenol A, BPA）、双酚F（Bisphenol F, BPF）、双酚S（Bisphenol S, BPS）联合或不联合ERI处理48小时的MCF-7细胞的全基因组DNA甲基化组分析结果（包含差异甲基化位点（Differentially Methylated Positions, DMPs）与差异甲基化区域（Differentially Methylated Regions, DMRs））；以及TCGA乳腺癌患者中雌激素受体阳性（ER-positive）乳腺癌组织与对应癌旁正常组织的全基因组DNA甲基化组分析结果（仅包含差异甲基化位点DMPs）。本数据集文件格式为XLSX，大小为2.310千字节。