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H3K27 Acetylation profile of hypothyroid NCoR1KO mice

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NIAID Data Ecosystem2026-05-17 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP108329
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资源简介:
We ablated the expression of the Nuclear Receptor Corepressor 1 specifically in mice livers and rendered them hypothyroid. Then we performed H3K27 acetylation CHIP-Seq. We found decreased H3K27ac in the livers of hypothyroid wild type and NCoR1KO mice. Therefore, we concluded that the thyroid hormone receptor may recruit histone deacetilases independently of NCoR1. Overall design: Examination of H3K27ac by Chip-Seq in euthyroid and hypothyroid Wt and NCoR1KO mouse
创建时间:
2017-09-23
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