Antiretroviral treatment: adherence and the influence of depression in users with HIV/Aids treated in primary care

ABSTRACT Adherence to treatment is one of the major challenges to HIV (Human Immunodeficiency Virus) treatment, being depression a factor that impacts on it. The research aimed to identify if depression interferes with adhesion. A multi-approach method for adherence, open interview and Beck Depression Inventory were used for depression screening. The relationship between depression and nonadherence was not found, although the prevalence of depression reached 22.24%. Some patients assume fear of stigma and difficulty in following antiretroviral treatment due to the drug adverse effects. Also a social protection network was perceived as crucial as was the necessity to build a care network.

摘要 治疗依从性是人类免疫缺陷病毒（Human Immunodeficiency Virus, HIV）治疗面临的主要挑战之一，而抑郁是影响治疗依从性的相关因素。本研究旨在明确抑郁是否会对治疗依从性产生干扰。研究采用多维度治疗依从性评估方法、开放式访谈以及贝克抑郁量表（Beck Depression Inventory）开展抑郁筛查。尽管抑郁患病率达到22.24%，但未发现抑郁与治疗不依从之间存在关联。部分患者坦言因畏惧病耻感以及药物不良反应带来的不适，难以坚持抗逆转录病毒治疗。此外，研究对象认为社会保护网络至关重要，同时也意识到构建照护网络的必要性。