Data and code archive for project "Tracing caffeine and its metabolite in wastewater to understand the spread of SARS-CoV-2"

This dataset/code archive included all the data and R codes that were used to explore the universal and robust wastewater biomarkers for population normalization in the SARS-CoV-2 wastewater-based epidemiology. There are nine R code files to produce figures and tables. The data included: Raw data of weekly biomarkers (caffeine, paraxanthine, and PMMoV) wastewater concentrations, weekly new COVID-19 case numbers, SARS-CoV-2 N1/N2 copies in wastewater, wastewater flow rate A total of 2,624 wastewater samples (41 weeks) were collected weekly from May 2021- April 2022 from 64 wastewater treatment plants across Missouri, US; pMMoV data was only available from Sep 13 2021-April 2022 for Missouri data; Additionally, 10 wastewater samples from 10 wastewater treatment plants across Wisconsin, US, for model validation. Downloaded Apple mobility data during the pandemic Flowrate and paraxanthine concentration, and SARS-CoV-2 N1/N2 copies during the flooding event at one WWTP in St. Louis in July 2022.