METHOD FOR BASE EDITING IN PLANTS
收藏国家林业和草原科学数据中心2023-02-12 更新2024-03-07 收录
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资源简介：
Provided relates to the field of genetic engineering. In particular， a method for base editing in plant is provided. More specifically， a highly efficient A to G base editing method for a target sequence in a genome of a plant (e.g.， a crop plant) by a guide RNA-directed CRISPR-adenine deaminase fusion protein and the plant and their progeny produced by the method are provided. Provided relates to the field of genetic engineering. In particular， a method for base editing in plant is provided. More specifically， a highly efficient A to G base editing method for a target sequence in a genome of a plant (e.g.， a crop plant) by a guide RNA-directed CRISPR-adenine deaminase fusion protein and the plant and their progeny produced by the method are provided.
本发明涉及基因工程领域，具体而言，提供了一种植物碱基编辑方法。更具体地，本发明提供了一种由向导RNA（guide RNA）引导的CRISPR-腺嘌呤脱氨酶融合蛋白（CRISPR-adenine deaminase fusion protein）介导的、针对植物（例如农作物）基因组靶序列的高效A→G碱基编辑方法，以及通过该方法获得的植物及其后代。
提供机构：
国家林业和草原科学数据中心
创建时间：
2023-02-12
