Additional file 7 of DNA methylation, combined with RNA sequencing, provide novel insight into molecular classification of chordomas and their microenvironment

Additional file 7. Supplementary tables: DMP - differentially methylated probes, DMR - differentially methylated regions, DEG - differentially expressed genes, GSEA - gene set enrichment analysis, MethExpr_Correlation - correlation of promoter methylation with gene expression, DEG_DMR_Correlation - correlation of differentially expressed genes with methylation in DMRs, DEG_DMR overrepresentation - Overrepresentation analysis of DEGs correlated with DMRs, WGCNA_modules_significance - statistical testing of WGCNA modules association with methylation clusters, Immune_deconvolution - statistical testing of immune cell deconvolution with methylation clusters, conumee - estimation of CNAs in chordoma samples, GSEAlm - GSEAlm estimate of gene expression across chromosomal bands in the whole genome.

附加文件7：补充表格，涵盖以下分析项：DMP：差异甲基化探针（differentially methylated probes, DMP）、DMR：差异甲基化区域（differentially methylated regions, DMR）、DEG：差异表达基因（differentially expressed genes, DEG）、GSEA：基因集富集分析（gene set enrichment analysis, GSEA）、MethExpr_Correlation：启动子甲基化与基因表达的相关性分析、DEG_DMR_Correlation：差异表达基因与差异甲基化区域内甲基化水平的相关性分析、DEG_DMR overrepresentation：与差异甲基化区域相关的差异表达基因的过度富集分析、WGCNA_modules_significance：加权基因共表达网络分析（WGCNA）模块与甲基化簇关联的统计学检验、Immune_deconvolution：免疫细胞反卷积与甲基化簇关联的统计学检验、conumee：脊索瘤样本拷贝数变异（copy number aberrations, CNAs）的评估、GSEAlm：全基因组染色体条带间基因表达水平的GSEAlm评估结果