官方服务：
资源简介：
To described the effects of BTK inhibitors on CART19
应用场景：
创建时间：
2023-03-16
相关数据集
Discovery of AS-1763: A Potent, Selective, Noncovalent, and Orally Available Inhibitor of Bruton’s Tyrosine Kinase
Although Bruton’s tyrosine kinase (BTK) has been recognized as a validated drug target for the treatment of B-cell malignances, the emergence of clinical resistance to the first-generation covalent BT
NIAID Data Ecosystem70
North America Bruton Tyrosine Kinase (BTK) Inhibitors Market
The North America Bruton Tyrosine Kinase (BTK) Inhibitors report provides a detailed analysis of emerging investment pockets, highlighting current and future market trends. It offers strategic insight
IMR REPORTS50
The BTK Inhibitor CC-292 shows activity in Mantle Cell Lymphoma and synergizes with Lenalidomide and NIK Inhibitors depending on NFκB mutational status
Mantle Cell lymphoma (MCL) were treated with the BTK inhibitor 1mM CC-292 for 48h We used microarrays to uncover the mechanisms underlying CC-292 activity in Mantle Cell lymphoma (MCL) Global RNA expr
NIAID Data Ecosystem40
Brutons tyrosine kinase in complex with compound 50.
Brutons tyrosine kinase in complex with compound 50. Descriptor: 1,2-ETHANEDIOL, N-[2-fluoro-6-(pyrrolidin-1-yl)phenyl]-N'-{3-[(2R)-1-(2-hydroxyethyl)-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-2-yl
Protein Data Bank Japan2024-03-13 更新50
Crystal structure of BTK kinase domain complexed with 6-(dimethylamino)-8-fluoro-2-[2-(hydroxymethyl)-3-[1-methyl-5-[[5-(morpholine-4-carbonyl)-2-pyridyl]amino]-6-oxo-3-pyridyl]phenyl]isoquinolin-1-one
Crystal structure of BTK kinase domain complexed with 6-(dimethylamino)-8-fluoro-2-[2-(hydroxymethyl)-3-[1-methyl-5-[[5-(morpholine-4-carbonyl)-2-pyridyl]amino]-6-oxo-3-pyridyl]phenyl]isoquinolin-1-on
Protein Data Bank Japan2023-09-20 更新40
