We employed mouse models with targeted deletion of the genes encoding Epac1 (Rapgef3) and Epac2 (Rapgef4) in combination with 2/3 partial hepatectomy to investigate the functional roles of Epac1 and E
This study focuses on the comprehensive analysis of the proteome in db/db mice, a model of type 2 diabetes mellitus (T2DM), using liquid chromatography coupled with mass spectrometry (LC-MSMS). The ai
Spliceosome dephosphorylation is essential control step that enables intron removal from pre-mRNA for the regulation of gene expression. However, the phosphatase that is biologically responsible has n
This study determined the influence of myeloid cell Trim59 deficiency on experimental stroke outcomes and the cerebral proteomic profile using myeloid cell Trim59 conditional knockout (Trim59-cKO) mic