SH1044669.10FU

UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.

UNITE数据库为基于DNA的物种假说（Species Hypotheses，SH）的界定、识别、传播与相关研究提供了统一的操作框架。国际核酸序列数据库中的所有真菌内部转录间隔区（Internal Transcribed Spacer，ITS）序列，通过应用一套动态距离阈值（0.5%~3.0%），被聚类至近似物种级别。所有物种假说均以数字对象标识符（Digital Object Identifier，DOI）的形式获得唯一且稳定的标识名称，其分类学与生态学注释信息均通过分布式网络第三方注释工作完成核验。每个物种假说都会结合其包含的所有序列的鉴定结果，尽可能匹配对应的分类单元名称及其分类层级（门、纲、目等）。针对每个物种假说，均会选取一条经自动或人工标注的序列作为其代表序列。这些代表序列已发布于（https://unite.ut.ee/repository.php），可供科研群体用于本地序列相似性搜索、下一代测序分析流程等科研场景。随着公共真菌ITS序列库规模的不断扩大，该系统与数据库将自动进行更新。