A high hepatic uptake of conjugated bile acids promotes colorectal cancer-associated liver metastasis

NIAID Data Ecosystem2026-03-14 收录

癌肝转移机制

胆汁酸代谢

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA901071 数据链接链接失效反馈

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资源简介：

Role of conjugated bile acids in promoting colorectal cancer liver metastasis by establishing tumor microenvironment

创建时间：

2022-11-13

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癌肝转移机制

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Pancreatic cancers (PC) are highly metastatic with poor prognosis, mainly due to delayed detection. We previously showed that PC-derived extracellular vesicles (EVs) act on macrophages residing in the

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胆固醇胆结石干预

胆汁酸代谢

Gypenosides (GPs), obtained from Gynostemma pentaphyllum (Thunb.) Makino, have been traditionally prescribed to treat metabolic disorders in Asians. This study assessed whether GPs could prevent litho

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DataSheet2_Transcriptomic study of gastrointestinal stromal tumors with liver metastasis.csv

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转录组生物标志物

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NIAID Data Ecosystem20

Unconjugated fecal bile acid composition and comparisons between the groups (n = 53).

胆汁酸代谢

肠道微生物标志物

Unconjugated fecal bile acid composition and comparisons between the groups (n = 53).

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single-cell RNA transcriptome sequencing revealed that androgen/AR signaling promotes neutrophil precursors proliferation in bone marrow. single-cell RNA transcriptome sequencing revealed that androgen/AR signaling promotes neutrophil precursors proliferation in bone marrow

癌肝转移机制

中性粒细胞发育调控

The liver is one of the most-favored distant metastatic sites for solid tumors, and interactions between cancer cells and components of the hepatic microenvironment are essential for liver metastasis

NIAID Data Ecosystem30

A high hepatic uptake of conjugated bile acids promotes colorectal cancer-associated liver metastasis

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