Ameliorative effects of fenugreek (Trigonella foenum-graecum) seed on type 2 diabetes

Abstract The hyperglycaemia defines features of type 2 diabetes (T2DM), which is a real time problem and poses a significant economic burden on the globe and is spreading like an epidemic. Currently it affects 384 million people on the globe and this number is expected to reach 592 million in 2035 as reiterated by International Diabetes Federation (IDF). By improving the quality of diet and decreasing the intake of sugary foods T2DM can be treated. Fenugreek seeds powder in sachet form of 20 g/day used to treat type 2 diabetes mellitus as a natural supplement. Anthropometric parameters of height, weight, age and BMI of T2DM patient was also calculated. In this study patients from Rawalpindi and Islamabad region were selected for study purpose. Blood sugar levels such as fasting blood glucose (FBG), random blood glucose (RBG), and HbA1c of both the groups (treated and control) were taken at baseline, after one month and at the end of study. When fenugreek seeds were given to T2DM patients significant decrease in their glucose levels were seen after 30 and then 60 days of treatment.

摘要：高血糖症（hyperglycaemia）是2型糖尿病（type 2 diabetes, T2DM）的核心特征，该疾病已是当下亟需应对的全球性问题，不仅给全球带来沉重经济负担，且如疫情般快速蔓延。据国际糖尿病联盟（International Diabetes Federation, IDF）披露，目前全球共有3.84亿人受2型糖尿病影响，预计到2035年这一数字将增至5.92亿。通过优化饮食结构、减少含糖食物摄入，可对2型糖尿病进行干预治疗。本研究以每日20g袋装胡芦巴籽粉（fenugreek seeds powder）作为天然补充剂，用于2型糖尿病的干预治疗；同时测算受试患者的人体测量学指标，包括身高、体重、年龄及身体质量指数（Body Mass Index, BMI）。本研究的研究对象选自拉瓦尔品第与伊斯兰堡地区的患者。分别于基线、干预1个月后及研究结束时，采集两组（干预组与对照组）患者的血糖指标，包括空腹血糖（fasting blood glucose, FBG）、随机血糖（random blood glucose, RBG）及糖化血红蛋白（HbA1c）。结果显示，向2型糖尿病患者给予胡芦巴籽粉干预30天后及60天后，其血糖水平均出现显著下降。