Amyloid fibril structures link CHCHD10 and CHCHD2 to neurodegeneration

PDB files, PDB Validation reports, and Cryo-EM maps for the reported structures of WT CHCHD10, S59L CHCHD10, WT CHCHD2, and T61I CHCHD2 N-terminal domain amyloid fibrils. Raw TEM and cryo-EM micrographs and confocal images.

本数据集涵盖野生型（Wild Type, WT）CHCHD10、S59L突变型CHCHD10、野生型CHCHD2以及T61I突变型CHCHD2的N端结构域淀粉样蛋白原纤维已报道结构对应的PDB（Protein Data Bank）文件、PDB验证报告及冷冻电镜（Cryo-Electron Microscopy, Cryo-EM）密度图，同时包含原始透射电子显微镜（Transmission Electron Microscopy, TEM）显微图像与共聚焦显微镜图像。